Cell line authentication by STR
Frequently Asked Questions

Is STR the only valid method for human cell line authentication?

STR is not the only possible method for cell line authentication. However, it is the most commonly used and the only one that has obtained international consensus. It is recommended by several official institutions such as the ISSCR Standards for Stem Cell Research (International Society for Stem Cell Research), the ATCC Standards Development Organization or the Elsevier Scientific guidelines for lab resources, to name a few.

How often should STR be performed on a cultured cell line?

The ISSCR encourages checking your cell line identity at least quarterly and ideally monthly for cells that undergo significant manipulations such as gene editing, clonal isolation, etc. It is also recommended when establishing the Master Cell Bank, at the end of studies and before publication. In addition, Stem Genomics recommends combining it with routine genomic stability testing (like our iCS-digital test) every 5 passages during culture and after stressing manipulations.

How much does it cost ?

The price is available on request and will vary depending on the quantities ordered. Bulk discounts are also available when ordering more than one type of assay at the same time.

Can you support stem cell researchers with other useful assays besides cell line authentication that we can integrate into our QC ?

In line with the ISSCR’s latest quality standard recommendations, Stem Genomics strongly recommends regularly checking the genomic stability of your stem cells during their time in culture with our digital PCR iCS-digital™ range. Mycoplasma testing is also critical for robust science and we have a digital PCR solution called Myco-digital that can do that for you.

Important announcement for our US clients: we have moved!

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Please note that we will be closed from July 12 to 16

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SAVE THE DATE: Thursday, November 7, 6pm CET/9am PDT/12 pm EDT.

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