Stem cell research scientists need reassurance concerning the genomic stability of the cells they are using in their experiments. The validity of their research work relies in part on the implementation of a robust genomic quality control system.
Traditional karyotyping methods alone will not always provide the level of sensitivity required to reliably detect the most common abnormalities found in stem cells.
In addition, they are generally not suited to regular testing at each step that cells are put under stress due to their processing lead times.
With these constraints in mind, Stem Genomics has developed a range of tests to match your specific requirements and put your mind at rest.
The iCS-digital™ range has been designed to target specific abnormalities relevant to hPSCs & hMSCs, as well as aneuploidy detection. These assays use highly sensitive digital PCR (dPCR) technology, ideal for small size CNV detection that other traditional methods like G-Banding will miss.
Detect over 92% of recurrent abnormalities in hPSCs in record-breaking time !
Detect over 80% of recurrent abnormalities in hMSCs in record-breaking time !
Detect aneuploidy in any
human cell type in
record-breaking time !
The Duo iCS-Karyo assay* will provide you with a combined G-Banding and iCS-digital PSC solution for assessing the genomic integrity of your cells with high precision.
* Only available in Europe and North America. Outside these geographical locations, you can combine your traditional G-Banding analysis with our iCS- digital™ PSC solution.
If you only need a G-Banding analysis to be performed, please follow this link.
The ultimate combined solution for hPSC in-process genomic stability testing
The Stem-Seq™ Panel enables stem cell scientists to look deeper into targeted regions of interest. Based on NGS technologies, the Stem-Seq™ Panel detects Single-Nucleotide Variants (SNVs) associated with cancer (including TP53, BCOR, etc.), but also selected variants specific to pluripotent stem cells and their impact on the natural development of cells in culture.
Look deeper into any human cell type and detect targeted SNVs & Indels
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