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Aneuploidy is a widespread abnormality with well-documented clinical complications. This chromosomal defect can be found in the cell lines you work on in your laboratories.
Traditional screening methods such as G-Banding or FISH can be helpful, but can turn out to be lengthy and costly for your organization.
On the other hand, digital PCR-based assays offer highly sensitive detection and fast turnaround time.
This led Stem Genomics to develop a specific aneuploidy detection solution for research scientists working on human cell lines.
The iCS-digital™ Aneuploidy test is composed of a set of 24 probes that target all 24 human chromosomes.
It allows the detection of whole chromosome gains and losses (trisomy, tetrasomy, monosomy, etc.).
Our digital PCR-based solution enables rapid and cost-effective screening for chromosomal abnormalities, delivering results in just 3 days from reception. It is ideal for routine monitoring of genomic stability.
This test is particularly useful to detect aneuploidy in adult stem cells, their differentiated derivatives and potentially any human cell type. However, for human embryonic and induced pluripotent stem cells, we recommend the iCS-digital™ PSC test and for hMSCs, the iCS-digital™ MSC test, specifically designed for these cell types.
Any human cell type
Any
gDNA
Cell pellet
Cells in fresh culture media (or in cell culture supernatant)
Room temperature
Dry ice
Room temperature
Aneuploidy of any of the 24 chromosomes: whole chromosome gains & losses
>20% (depending on sample quality)
2-3 days after sample reception
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IRMB – Hôpital Saint Eloi
80 avenue Augustin Fliche
34295 Montpellier Cedex 5 – France
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