Some publications have validated studies with iCS-digital™ PSC used as the sole genomic stability test (Stem Cell reports, Stem Cell Research and therapy, Cells and Current Eye Report (Brot et al. 2022, Duchesne de Lamotte et al. 2021, Roudaut et al. 2021, Rupendra Shrestha et al. 2020. to name a few)). It really depends on the context of your research and the reviewers.
You can, at the amplification and maintenance stage, or during clone screening. However, we strongly recommend associating the iCS-digital™ PSC test with G-Banding at the acquisition of a new cell line or banking stage or at the end of the process. G-Banding will provide a pangenomic view (balanced and unbalanced translocations, aneuploidies, inversions, duplications/deletions > 5-10 Mb) that you won’t get from a very targeted digital assay such as iCS-digital™ PSC. Ideally, they should both be combined, as in the Duo iCS-Karyo assay, another genomic stability assay offered by Stem Genomics.
Not at all. It is a very straightforward report that gives you a clear indication of the abnormalities found and the CNV values for each targeted region. A sample report is available on request.
The price will depend on the number of samples you need to test, and you can benefit from volume-based discounts.
Stem Genomics has designed another similar assay for detecting abnormalities in Mesenchymal Stromal Cells (MSCs) called iCS-digital™ MSC and a standard assay for any other human cell type called iCS-digital™ Aneuploidy.
In accordance with the ISSCR’s latest quality standard recommendations, Stem Genomics strongly recommends regularly checking the identity of your stem cells during their time in culture with our STR assay. Mycoplasma testing is also critical for robust science and we have a digital PCR solution called Myco-digital that can do that for you.
As of July 17, our new address will be:
400 Park Offices Drive, Room 105
Research Triangle Park, Durham, North Carolina 27713
Please note that we will be closed from July 12 to 16
during the transition.
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Join us LIVE for a Q&A session on the latest iCS-digital™ PSC upgrade.
Find out what it means for you and ask all your questions
Juline VINCENT our R&D Project Manager and Digital PCR expert will answer you LIVE.
SAVE THE DATE: Thursday, November 7, 6pm CET/9am PDT/12 pm EDT.
Join us LIVE for our webinar!
Best Practices: Making your hPSC Quality Control workflow more efficient
Join Juline VINCENT, our R&D Project Manager, as she presents efficient quality control strategies specifically designed to address the unique characteristics of pluripotent stem cells.
Thursday, October 23, 12:00 PM EST / 6:00 PM CET
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